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Faculty of Medicine
Document Details
Document Type
:
Article In Journal
Document Title
:
Hodgkin's lymphoma with exuberant granulomatous reaction.
Hodgkin's lymphoma with exuberant granulomatous reaction.
Document Language
:
English
Abstract
:
We report a 36-year-old woman, presented with cervical lymphadenopathy and low-grade fever. Two fine needle aspiration cytology and one excisional biopsy were performed in the referral hospital, all showed granulomatous lesions without necrosis. A tentative diagnosis of tuberculosis was made, and she started on antituberculous treatment. However, there was no clinical improvement. She presented to our institution one year after the initial diagnosis, and a new biopsy from the cervical lymph node revealed effacement of the whole node by marked non-necrotizing granulomatous reaction. However, there were scattered large cells with few classic Reed-Sternberg cells between the granulomas. Immunohistochemistry reveals strong reaction of CD15 and CD30, and negative staining for CD45RB, CD45RO, and CD20. These findings confirmed the diagnosis of Hodgkin's lymphoma with remarkable granulomatous reaction that almost masked the malignant component. She was treated with chemotherapy, and she showed an excellent response.
ISSN
:
17143374
Journal Name
:
Saudi Med J.
Volume
:
27
Issue Number
:
12
Publishing Year
:
2006 AH
2006 AD
Article Type
:
Article
Added Date
:
Sunday, April 11, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
جودة المغربي
Al-Maghrabi, Jaudah
Investigator
Doctorate
Files
File Name
Type
Description
26375.doc
doc
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